Scientists explore process to utilise tobacco crop as biomass

The study, led by researchers at the National Tobacco Cultivation, Physiology and Biochemistry Research Centre, demonstrates that tobacco leaves can be converted into bioethanol through a simple process.
By autoclaving fresh tobacco leaves in water under moderate temperature and pressure, scientists achieved over 65% biomass solubilisation, creating a nutrient-rich solution suitable for direct microbial fermentation.
This streamlined approach eliminates the energy-intensive chemical pretreatments typically required for traditional lignocellulosic biorefineries.
The method capitalises on tobacco's unique composition - rich in water-soluble carbohydrates and nitrogen whilst containing relatively low lignin levels - making it far easier to process than conventional energy crops like switchgrass or Miscanthus.
The environmental implications are striking. Life cycle assessments conducted by the research team suggest that if tobacco were cultivated on marginal or degraded lands globally, it could potentially produce approximately 573 billion gallons of ethanol annually.
More significantly, tobacco-derived ethanol demonstrates roughly 76% lower greenhouse gas emissions and energy consumption compared to conventional lignocellulosic fuels.
Performance comparisons indicate tobacco's competitive potential.
Laboratory trials show tobacco can yield several hundred litres of ethanol per tonne of biomass, with cultivation producing 10–15 dry tonnes per hectare under intensive management.
This translates to potential ethanol production of a few thousand litres per hectare, placing it within the range of established energy crops like sorghum and switchgrass.
The transformation addresses multiple challenges simultaneously. As public health initiatives reduce tobacco demand for smoking products, this alternative application offers tobacco farmers economically viable options whilst advancing climate goals.
The approach aligns with the World Health Organisation's Framework Convention on Tobacco Control, which encourages providing alternative livelihoods for tobacco farmers.
However, significant hurdles remain. Nicotine toxicity presents challenges for microbial fermentation, requiring either detoxification processes or specially adapted microorganisms.
The technology currently sits at an early laboratory stage, necessitating pilot-scale projects and comprehensive techno-economic analyses before commercial viability can be established.
Researchers emphasise the importance of cultivating tobacco on marginal lands to avoid competition with food crops, whilst implementing sustainable land management practices to prevent soil degradation and protect biodiversity.
Source: Yin, Q., Zhu, Z., Chen, Y., & Yang, M. (2025). Leveraging tobacco for a low-carbon biorefinery. Frontiers in Plant Science.
















